Affron®

The Mood & Emotional Wellbeing Extract

A clinically studied, standardised saffron (Crocus sativus L.) extract that improves mood, emotions and sleep.

What is Affron® Good For?

Affron® is a patented extract of saffron that is guaranteed to contain at least ≥3.5% lepticrosalides (the main bioactive compound). Backed by multiple peer-reviewed human studies, Affron® has been shown to improve mood and emotions related to stress, reduce anxiety, and improve sleep quality.

 

Affron® supplementation may lead to:

  • Improvements in mood and emotions related to stress
  • Reduced anxiety
  • More restful, restorative sleep
  • Improvements during menopause by reducing depression and anxiety

What is Saffron?

Saffron is derived from the dried stigmas of the Crocus sativus flower, known as the world’s most precious spice. Traditionally used in Mediterranean and Middle Eastern medicine, saffron has been associated with improved mood and better sleep quality.

 

Affron® stands apart from generic saffron powders due to its patented extraction and standardisation method, ensuring consistent levels of bioactive compounds that deliver reproducible results in line with clinical data.

What is the Recommended Daily Dose of Affron®?

Human clinical studies have demonstrated benefits with 28 mg per day, taken consistently over 4-8 weeks. This low, effective dose makes Affron® one of the most efficient saffron extracts available.

Things to Know

Extracted from

Crocus sativus L. (saffron stigmas)

Technology

Patented extraction & standardisation method (to ensure at least ≥3.5% lepticrosalides)

Region

Cultivated in Spain under strict quality controls

Data

Supported by multiple peer-reviewed human clinical trials on mood, sleep, and menopause

Affron® in Detail

Clinical Dose
Clinical Dose

28 mg

Source
Source

Saffron stigmas (Crocus sativus L.)

Technology
Technology

Patented Affron® extraction process ensuring  ≥3.5% lepticrosalides for consistent efficacy.

Key Benefits
Key Benefits
  • Clinically shown to improve mood and emotions related to stress
  • Reduces anxiety
  • Reduces depression and anxiety during menopause
  • Improves sleep quality and restorative sleep by increasing evening melatonin levels
  • Proven efficacy at a low daily dose (28 mg)
Data
Data

Multiple human clinical studies published in peer-reviewed journals

Your Questions About Affron®

Reach us arrow_forward
Affron® is a patented, standardised saffron extract clinically studied for its effects on mood, stress, and sleep.
It improves mood, reduces anxiety, enhances sleep quality, and contributes to a better emotional wellbeing.
Affron® is backed by multiple clinical trials, standardised for lepticrosalides, and sourced sustainably from Spanish saffron, ensuring consistency and traceability.
Affron® is safe and well tolerated at the clinical dose of 28 mg. No significant side effects have been reported.
Most clinical studies show improvements in mood and wellbeing within 4–8 weeks of daily supplementation.

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References

The Science That Supports Us

Cognitive and Neurological Support

Lopresti, A.L. et al. (2025) ‘An examination into the effects of a saffron extract (Affron) on mood and general wellbeing in adults experiencing low mood: A randomized, double-blind, placebo-controlled trial’, The Journal of Nutrition, 155(7), pp. 2300–2311. doi:10.1016/j.tjnut.2025.05.024.

Mental Health

Lopresti, A.L. and Smith, S.J. (2021) ‘The effects of a saffron extract (affron®) on menopausal symptoms in women during perimenopause: A randomised, double-blind, placebo-controlled study’, Journal of Menopausal Medicine, 27(2), p. 66. doi:10.6118/jmm.21002.

Nerve Repair

Lopresti, A.L., Smith, S.J. and Drummond, P.D. (2021) ‘An investigation into an evening intake of a saffron extract (affron®) on sleep quality, cortisol, and melatonin concentrations in adults with poor sleep: A randomised, double-blind, placebo-controlled, multi-dose study’, Sleep Medicine, 86, pp. 7–18. doi:10.1016/j.sleep.2021.08.001.

Immune System Support

Lopresti, A.L. et al. (2020) ‘Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: A randomized, double-blind, placebo-controlled trial’, Journal of Clinical Sleep Medicine, 16(6), pp. 937–947. doi:10.5664/jcsm.8376.