Ingredient
Alpha Lipoic Acid
The Universal Antioxidant
A clinically studied antioxidant that improves cellular energy production, nerve function, and metabolic homeostasis. Both water- and fat-soluble — the "universal antioxidant."
What is Alpha Lipoic Acid Good For?
Alpha Lipoic Acid (ALA) is a naturally occurring compound produced in small amounts by multiple organs, also found in spinach, broccoli, and organ meats. Known as the "universal antioxidant," it exhibits both water and fat solubility.
Potential benefits of supplementation
- Improved blood sugar metabolism
- Increased energy production in mitochondria
- Better nerve function in diabetic individuals
- Enhanced liver detoxification pathways
- Improved antioxidant defense against age-related decline
- Enhanced mitochondrial function through recycling of vitamins C & E
What is Alpha Lipoic Acid?
ALA functions as a disulfide compound central to mitochondrial energy metabolism. It serves as a cofactor helping enzymes convert nutrients into energy while neutralizing free radicals.
Supplemental forms provide higher levels than dietary sources and have been extensively researched for glucose metabolism and diabetic neuropathy.
Recommended Daily Dose
600 mg
Clinical studies indicate 600 mg daily improves nerve functions, antioxidant defense, and metabolic processes. Lower doses (100–300 mg) are commonly used for maintaining ALA levels.
Alpha Lipoic Acid in Detail
- Clinical Dose
- 600 mg
- Source
- Endogenously produced; also found in spinach, broccoli, organ meats
- Technology
- Dual solubility (fat- and water-soluble); available as racemic ALA or R-ALA
- Key Benefits
- Universal antioxidant working in all tissues
- Supports blood sugar homeostasis and insulin sensitivity
- Protects nerves and supports neuropathic health
- Recycles vitamins C & E, extending antioxidant protection
- Enhances mitochondrial energy production
- Data
- Supported by peer-reviewed human clinical trials, particularly in nerve health and metabolic function.
Supports
Your Questions About Alpha Lipoic Acid
What is Alpha Lipoic Acid?
ALA is a naturally occurring compound that helps enzymes convert nutrients into energy while acting as a universal antioxidant.
What are the benefits of Alpha Lipoic Acid?
Supports nerve health, balances blood sugar, enhances antioxidant defense, and contributes to energy metabolism.
How is Alpha Lipoic Acid different from other antioxidants?
Unlike most antioxidants, ALA is both water- and fat-soluble, allowing it to work in every part of the cell and regenerate other antioxidants.
Are there any side effects?
Generally well tolerated; higher doses may cause mild digestive discomfort. Individuals with diabetes should consult healthcare providers due to blood sugar-lowering effects.
Can Alpha Lipoic Acid be taken with other supplements?
Yes; ALA complements vitamins C & E and works synergistically with nutrients supporting mitochondrial processes.
The Science That Supports Us
- 1Liu, J. (2007). The mitochondrial nutrient alpha-lipoic acid and age-associated cognitive dysfunction. Neurochemical Research, 33(1), pp. 194–203.
- 2Vallianou, N., Evangelopoulos, A. and Koutalas, P. (2010). Alpha-lipoic acid and diabetic neuropathy. The Review of Diabetic Studies, 6(4), pp. 230–236.
- 3Shay, K.P. et al. (2009). Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta, 1790(10), pp. 1149–1160.
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